If you are a health care provider who wants to bill Medicaid for your services, you must enroll as a participating provider through the provider enrollment portal. The portal is a one-stop shop for providers:
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Enroll or re-enroll
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Revalidate enrollment
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Update enrollment information
MPRIME - New Provider Enrollment Portal Maryland Medicaid will be transitioning from ePREP to the Maryland Provider Registration and Information Management Enterprise (MPRIME) portal in October 2026.